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The SSD market has been characterized by two distinct and competitive product segments: desktop and notebook computers.[40] Desktop-class flash-based drives were originally designed for laptops. These drives use the SATA protocol, have a large capacity, and a correspondingly low price. For example, the 100 GB SanDisk Cruzer line of drives are available for just $99;[88] however, the drives are of the MLC variety and typically perform no better than a traditional hard drive. According to IDC, the largest segment of the flash-based drives is the notebook market, which is currently dominated by SanDisk and Western Digital Corporation's WD brand, and these drives use the Parallel ATA interface. The 90 GB, 120 GB and 180 GB (and higher) SanDisk Cruzer Black line of drives are available for $189, $299 and $399, respectively;[88] whereas the WD Black line of drives, listed at around $350,[89] are available for a lower price than the Cruzer line. The WD line of drives use a combination of SLC flash and hard disk drives, in a configuration more comparable to the old MFM hard drives.[85][86][87][88]
In the past, flash has typically offered more long-term performance stability than hard drives. Flash-based SSDs have outperformed hard disk drives in testing, and exhibit significantly better endurance and reliability.[37][89] However, early flash-based SSDs exhibited relatively low performance, limited endurance and unacceptable error rates.[37][37][38] In contrast, flash-based SSDs have evolved from being expensive and unreliable up-market devices into a mainstream enterprise product.[37][90] The increased reliability, endurance, and performance of flash-based SSDs have made them a viable alternative to hard drives in a wide variety of applications, and even in the consumer market.[37][37][38] However, flash-based SSDs have yet to be able to match the performance, reliability and endurance of hard drives. As of 2018, flash-based SSDs are commonly used in laptops and enterprise desktops;[37][89] they are used in high performance desktop computers, in servers, in cloud storage services, and in data centers, where they can sometimes be used in place of spinning disks or as an alternative to a spinning disk.[91]
As further set forth in Section 1.71 of the Orange Book [1][5], a sponsor may make or use a drug substance from time to time for purposes other than making a drug product. It is understood that such activities may be for the purpose of performing research and providing a supply of material for the sponsor's own product development efforts, or for the purpose of developing a process for manufacturing a drug product.
Some applications, such as Java, require that the application directories and libraries are updated to a newer version before the user can update. However, there are some applications that are not explicitly API-specific, such as the X Window System, the X server source code, are automatically updated as required. 827ec27edc